Cardiovascular Risk Screening / Assessing Endothelial Dysfunction

• Cardiovascular Risk Screening
• Hypertension
• Coronary artery disease
• History or family history of heart disease, of stroke, heart attack or angina Low, Intermediate, or high Framingham risk score


• Patients undergoing preventative health evaluations
• Metabolic Disorders
• Diabetes Mellitus (Type 1 & 2)
• Metabolic Syndrome
• Obesity and insulin resistance
• Diabetic foot prevention


• Those seeking proof of vascular improvements from their treatments
• Autoimmune or Inflammatory Vascular Conditions
• Vasculitis
• Endothelial activation syndrome


• Pulmonary Conditions
• Pulmonary hypertension
• Sleep apnea (with vascular component)


• Neurovascular and Cognitive Conditions
• Alzheimer’s disease (vascular contribution)
• Vascular dementia
• Stroke history or risk


• Renal and Hepatic Conditions
• Renal Failure (CKD)
• Portal hypertension
• Pre-transplant vascular evaluation


• Reproductive Health
• Pregnancy-induced hypertension (PIH)
• Pre-eclampsia risk stratification
• Erectile dysfunction (ED) as a marker of systemic vascular damage


• Contraindications:
• Anyone diagnosed with Raynaud’s Disease.

• You sit and relax in a temperature-controlled room.
• We apply brief, safe pressure on your arm with a cuff to stimulate temporary blood flow restriction.
• Our infrared camera captures the temperature rebound of your fingertips-an indicator of vascular reactivity.
• The entire test takes just 15 minutes.
• You receive a detailed report with TR, RVT, and RNV values.
  • TR (Temperature Rebound) which indicates endothelial vasomotor recovery
  • RVT (Total Vascular Reactivity) which measures total vascular function.
  • RNV (Neurovascular Reactivity) which identifies autonomic/sympathetic nervous response
  
  

What do the results mean?

• Excellent Reactivity: Strong endothelial function, low risk.
• Reduced Reactivity: Vascular Dysfunction; further monitoring, or intervention may be needed.

The endothelium is the thin layer of cells lining the interior of every vessel in the circulatory system. It plays a central role in blood pressure regulation as well as thermoregulation, blood clotting, inflammation, edema, and control of passage to tissues in and out from the blood. Impaired function is characterized by a disturbed endothelium-dependent vasodilation and decreased bioavailability of nitric oxide. Endothelial dysfunction is for example an early feature in patients with hypertension and hypercholesterolemia.

Endothelial dysfunction is one of the key events in the development of atherosclerosis and is considered to be one of the first pathological symptoms in disease progression. It has also been proven in patents with type I or type II diabetes, systemic sclerosis, preeclampsia, hypertension, as well as other cardiovascular related diseases.

Studies have demonstrated that skin blood flow properties correlate well with the general condition of the endothelium. The skin is an easily accessible organ and provides clinicians with an excellent model for testing endothelial function in everyday work.

Endothelial dysfunction is one of the first changes in the body that signals increased risk for heart disease, stroke, diabetes complications, and even cognitive decline. Being an early marker, the possibility to use objective tests to assess endothelial function in different patient groups is of great interest. Early knowledge of endothelial dysfunction may assist in predicting cardiovascular risk and evaluating the outcome of treatment.

Studies have demonstrated that skin blood flow properties correlate well with the general condition of the endothelium. The skin is an easily accessible organ and provides clinicians with an excellent model for testing endothelial function in everyday work.